Vortioxetine Related

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Vortioxetine is the non-proprietary name for an antidepressant used to treat major depressive disorder (MDD) and, off-label, a range of other conditions, including chronic pain, anxiety, sleeping disorders, and so forth.

Most patients buy Vortioxetine under the brand name Trintellix. Prior to 2016, Trintellix was known as Brintellix, but the name was changed to prevent confusion with another medication. Regardless of whether one buys Vortioxetine, Brintellix, or Trintellix, it's all the exact same medication.

Vortioxetine is an atypical antidepressant in the serotonin modulators and stimulators class, or SMS. Like most antidepressants it inhibits the uptake of serotonin; unique to the SMS class, it also stimulates transmission of serotonin at a number of receptors.

Patients can only buy Vortioxetine in three strengths; 5 mg, 10 mg, or 20 mg tablets. 20 mg per day, regardless of the condition being treated, should not be exceeded without explicit doctor instruction.

Administration Guidelines

This product comes in tablets, which are taken once per day with or without food as desired. Individuals who have stomach upset after taking tablets may find relief taking them on a full stomach.

Around half of patients buy Vortioxetine to treat major depressive disorder, or MDD. In this application the medication provides numerous benefits:

  • Improved energy
  • Increased interest
  • Better impulse control
  • Improved control of thoughts
  • Better focus and clarity of thought
  • Fewer mood swings

And treatment is fairly simple:

  • Most patients are started on 10 mg per day.
  • After a couple of weeks, assuming no adverse effects develop, dosage is increased to 20 mg per day.
  • Most patients find 20 mg per day is adequate.
  • Treatment may continue for up to 9 months.

It takes about a month of treatment for full benefit to be seen. In clinical trials, patients taking Vortioxetine recovered from depression and had fewer relapses, assuming treatment continued for several months, than those taking a placebo. Those under age 18 or over age 65 may require modified dosing.

Treatment is much more variable in other conditions; the medication can be used long-term to manage chronic issues, or short-term---even as-needed---to manage flare-ups or acute conditions. For example, it can be used long-term to manage anxiety or as-needed to prevent panic attacks. Patients will need to speak with a doctor for the ideal dosage and treatment schedule.

Potential Complications

Side effects appear to be largely dose-dependent; the more Vortioxetine taken, the greater the likelihood of side effects and at greater severity. Most, however, are fairly mild and transient. Patients concerned about side effects should speak with a doctor about adjusting dosage, or alternative medications.

One side effect than concerns a lot of individuals is sexual dysfunction, an issue associated with all antidepressants. In trials patients taking Vortioxetine experienced sexual dysfunction more often than those taking placebo, but significantly less often than most other antidepressants. Those who do experience some form of sexual dysfunction may be able to alleviate it to some extent with other medications, like Viagra. Sexual side effects are nearly always reversible when treatment ends.

Those who buy Vortioxetine should be aware that this medication can have serious interactions with other medications, notably MAO inhibitors and NSAIDs like ibuprofen or aspirin. MAO inhibitors should not be taken two weeks before or three weeks after taking Vortioxetine. NSAIDs taken during treatment increase risk of unusual bleeding. Other medications can have lesser effects; check with a doctor or pharmacist before mixing treatments.

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Our clients will need a prescription to buy Vortioxetine. If you don't have one, our online doctor may be able to issue one. Simply add the desired product to your cart, begin checkout, and answer the questions on the following page to see if you qualify. There is no charge for our online doctor services.

Patients who already have a prescription to buy Vortioxetine will be provided with options to transfer it to us after completing checkout.

If you have any questions or need help with your order, please don't hesitate to let us know.



**Important note for patrons: The information on this page is not official label or safety information as written by the manufacturer or reviewed by the FDA. We only list for sale and refer orders to our affiliates for medications approved in the country where they are licensed, and any product requiring a prescription must be sold under the direction of a licensed physician.
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